Priscila Kosaka – Bionanomechanics Lab

Bionanomechanics group develops a technology for regulating liquid transport at the nanoscale with high precision

Our PhD students Javier Escobar and Juan Molina have been able to control the transport of extremely small amounts of liquids, in the order of zeptoliters (1 zL = 10-21 L), when these flow along resonant nanofluidic channels. Álvaro San Paulo, responsible for the work, explains: “What we have achieved is to measure with precision…

Position	RESEARCHER
Email	priscila@imm.cnm.csic.es
Phone	+34 91 806 07 00
Website	scholar.google.com
Research Works Research Patents	Research Works Nanomechanical Sensing for Mass Flow Control in Nanowire-Based Open Nanofluidic Systems Square Membrane Resonators Supporting Degenerate Modes of Vibration for High-Throughput Mass Spectrometry of Single Bacterial Cells High-Throughput Mass Measurement of Single Bacterial Cells by Silicon Nitride Membrane Resonators Detection Limits in Nanomechanical Mass Flow Sensing for Nanofluidics With Nanowire Open Channels Multifrequency Nanomechanical Mass Spectrometer Prototype for measuring viral particles using optomechanical disk resonators High-throughput determination of dry mass of single bacterial cells by ultrathin membrane resonators Hydrodynamic assisted multiparametric particle spectrometry Optomechanical detection of vibration modes of a single bacterium Effects of energy metabolism on the mechanical properties of breast cancer cells. Mechano-Optical Analysis of Single Cells with Transparent Microcapillary Resonators Development of a methodology for reversible chemical modification of silicon surfaces with application in nanomechanical biosensors Effect of surface stress induced curvature on the eigenfrequencies of microcantilever plates Optimization of the readout of microdrum optomechanical resonators Ultrasensitive detection of HIV-1 p24 antigen by a hybrid nanomechanical-optoplasmonic platform with potential for detecting HIV-1 at first week after infection Mass and stiffness spectrometry of nanoparticles and whole intact bacteria by multimode nanomechanical resonators Spatially Multiplexed Micro-Spectrophotometry in Bright Field Mode for Thin Film Characterization Highly sensitive measurement of liquid density in air using suspended microcapillary resonators Advances and Challenges to Bring Nanomechanical Biosensors to Biochemistry Labs and Clinical Use How two-dimensional bending can extraordinarily stiffen thin sheets Spatially multiplexed dark-field microspectrophotometry for nanoplasmonics Label-Free DNA-Based Detection of Mycobacterium tuberculosis and Rifampicin Resistance through Hydration Induced Stress in Microcantilevers Detection of cancer biomarkers in serum using a hybrid mechanical and optoplasmonic nanosensor Hydration Induced Stress on DNA Monolayers Grafted on Microcantilevers Monitoring swelling and deswelling of thin polymer films by microcantilever sensors Physics of Nanomechanical Spectrometry of Viruses Atomic force microscopy reveals two phases in single stranded DNA self-assembled monolayers Tackling Reproducibility in Microcantilever Biosensors: A Statistical Approach for Sensitive and Specific End-point detection of Immunoreactions Biosensors based on nanomechanical systems Quantification of the surface stress in microcantilever biosensors: revisiting Stoney's equation Imaging the surface stress and vibration modes of a microcantilever by laser beam deflection microscopy Challenges for nanomechanical sensors in biological detection Monitoring the hydration of DNA self-assembled monolayers using an extensional nanomechanical resonator Shedding Light on Axial Stress Effect on Resonance Frequencies of Nanocantilevers Observation of spermidine-induced attractive forces in self-assembled monolayers of single stranded DNA using a microcantilever sensor Simultaneous imaging of the topography and dynamic properties of nanomechanical systems by optical beam deflection microscopy High throughput optical readout of dense arrays of nanomechanical systems for sensing applications Research Patents METHOD FOR OBTAINING THE ABSORPTION POSITION, MASS AND RIGIDITY OF A PARTICLE ESPECTROFOTOMETRO UN SISTEMA PARA APLICACIONES DE BIODETECCIÓN MÉTODO Y SISTEMA DE CARACTERIZACIÓN DE ESTRUCTURAS NANO Y MICRO MECÁNICAS Method for bionalysis of nucleic acids in a sample and biosensor for its implementation.

Bionanomechanics Lab IMN CSIC

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Priscila Monteiro Kosaka

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